How Microdosing is Useful for Pain Relief Microdosing is a form of taking small doses of psychedelics to reduce the risk of adverse reactions and to experience some psychoactive effects. It can be done with psilocybin or other substances. Why do microdosing? Microdosing can be done because of the benefits of psychedelics, such as Psilocybin can help ease anxiety and depression, reduce cigarette smoking, and improve your sense of well-being. It is not known how microdosing works exactly, but it may work by increasing the amount of serotonin in the brain. There are no reported physical or psychological side effects from microdosing with psilocybin or other substances. Microdosing is a technique that involves taking very small doses of a psychedelic substance. It is believed that microdosing can help alleviate chronic pain. For example, it has been found to reduce the frequency of migraines in some people. In this section, we will discuss what microdosing is and how it can be beneficial